Wednesday 04/03/2026

• Expands global footprint to Singapore, gaining access to Asia-Pacific region to support research, clinical development and partnering activities
• Forms strategic partnership with A*STAR to accelerate advancement of innovative ophthalmic therapies and science
• Unveils second pipeline program, a next-generation retinal pigment epithelium (RPE) cell therapy to address significant unmet needs of patients with center-involving geographic atrophy (GA)
   

• Expands to Singapore and appoints Singapore site head. Complementing its UK science origins and US infrastructure, Cirrus has now established an R&D site in Singapore, further expanding its global footprint and gaining access to Asia-Pacific, one of the world’s fastest-growing biopharma markets. Si Hui Tan, PhD has been appointed as Director, Pipeline and Site Head, Singapore. Dr. Tan most recently led the first-in-class liver regeneration program at Lerna Biopharma, a multi-site biotech where she was also a founding member. Dr. Tan holds a PhD in Cancer Biology from Stanford University.
   

• Forges A*STAR collaboration to develop cutting edge ophthalmic assets. Related to its Singapore expansion, Cirrus has entered into a strategic partnership with the Agency for Science, Technology and Research (A*STAR), Singapore’s lead public sector R&D agency. This multi-million dollar collaboration will accelerate advancement of innovative ophthalmic assets, including Cirrus’ second pipeline program. The collaboration will be led by Associate Professor Xinyi Su, PhD, MBChir, Executive Director of the Institute of Molecular and Cell Biology (IMCB, A*STAR) and Senior Consultant Ophthalmologist, National University Hospital (NUH).
   
• Unveils second pipeline program, a novel RPE cell therapy. Cirrus has also unveiled its second pipeline program, a next-generation RPE (retinal pigment epithelium) cell therapy for the treatment of center-involving geographic atrophy (GA). This novel RPE cell therapy could be intrinsically fitter to function and survive in the hostile GA environment. The program’s differentiated profile has the potential for class-leading vision restoration. Cirrus also continues to advance its lead program toward the clinic, a novel ocular gene therapy designed to restore IRAK-M, so as to prevent AMD progression and preserve central vision. Together, these therapeutic programs afford potential treatments covering the different stages of AMD disease.